We'd like to learn Recurrent mutations in aspects of
- Distribution of the recurrent mutations
- comparison of missense and nonsense distribution
- relationship with
- expression level
- cohorts (or cancer sub types)
- effects
in protein protein network
Goals
mutation & methylation
BG
The recurrent nonsense mutations in P53 is at or adjacent to methylation sites.
Does this apply to other recurrent mutations?
Results1
Sequence analysis of p53 mutations
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di-nucleotide
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