Recurrent mutations
- Two sources can be responsible for the recurrence of a cancer.
- Firstly, the mutation preference on a DNA level.
- Secondly, the selection preference on a protein level
- Plan: remove the DNA level preferences.
Background mutation rate? for each type?
LS0tCnRpdGxlOiAiQmFja2dyb3VuZCBtdXRhdGlvbiByYXRlIgpvdXRwdXQ6IGh0bWxfbm90ZWJvb2sKLS0tCgojIFJlY3VycmVudCBtdXRhdGlvbnMKCi0gVHdvIHNvdXJjZXMgY2FuIGJlIHJlc3BvbnNpYmxlIGZvciB0aGUgcmVjdXJyZW5jZSBvZiBhIGNhbmNlci4gIAogICAgLSBGaXJzdGx5LCB0aGUgbXV0YXRpb24gcHJlZmVyZW5jZSBvbiBhIEROQSBsZXZlbC4gIAogICAgLSBTZWNvbmRseSwgdGhlIHNlbGVjdGlvbiBwcmVmZXJlbmNlIG9uIGEgcHJvdGVpbiBsZXZlbAoKLSBQbGFuOiByZW1vdmUgdGhlIEROQSBsZXZlbCBwcmVmZXJlbmNlcy4gIAoKQmFja2dyb3VuZCBtdXRhdGlvbiByYXRlPyBmb3IgZWFjaCB0eXBlPwo=