24 May 2017

Background

World trend of cancer

  • Incidence rates are increasing
    • Especially for developed countries

  • Mortality rates are decreasing
    • ~20% decline for most cancer types
    • Advancements in Early detection & medical resources But not a cure

Drivers - incompleted

Goal

  • Analysis cancer-causing mutations from structure perspective

  • driver mutation predictor

  • rarely mutated cancer genes